SCHEMBL22929973

SCHEMBL22929973

c1ccc2c(c1)-c1cccnc1-c1ccccc1-c1cccnc1-2

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 2/20 0.67
CTSL P07711 1/20 0.67
CTSS P25774 1/20 0.67
PTPN13 Q12923 1/20 0.67
TDP1 Q9NUW8 3/20 0.61
KMT2A Q03164 2/20 0.61
MEN1 O00255 1/20 0.61
THRB P10828 1/20 0.61
BLM P54132 1/20 0.61
TDP2 O95551 2/20 0.54
NSD2 O96028 2/20 0.54
PAX8 Q06710 2/20 0.54
ABL1 P00519 1/20 0.54
PLCG1 P19174 1/20 0.54
CES1 P23141 1/20 0.54
RIN1 Q13671 1/20 0.54
GAA P10253 1/20 0.54
ALDH1A1 P00352 1/20 0.50
CDC25B P30305 3/20 0.48
S100A4 P26447 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11910213 1.00 PTPRC (0.67) PTPRCCTSLCTSSPTPN13TDP1
SCHEMBL14935529 1.00 PTPRC (0.67) PTPRCCTSLCTSSPTPN13TDP1
SCHEMBL28420415 1.00 PTPRC (0.67) PTPRCCTSLCTSSPTPN13TDP1
SCHEMBL22929974 0.92 PTPRC (0.67) PTPRCCTSLCTSSPTPN13TDP1
SCHEMBL12854077 0.87 PTPRC (0.53) PTPRCCTSLCTSSPTPN13TDP1
SCHEMBL12854121 0.85 PTPRC (0.57) PTPRCCTSLCTSSPTPN13TDP1
SCHEMBL22930033 0.85 TDP1 (0.62) PTPRCCTSLCTSSPTPN13TDP1
SCHEMBL14380254 0.85 TDP1 (0.70) PTPRCCTSLCTSSPTPN13TDP1
SCHEMBL2910234 0.85 TDP1 (0.70) PTPRCCTSLCTSSPTPN13TDP1
SCHEMBL19764660 0.82 ALDH1A1 (0.68) PTPRCCTSLCTSSPTPN13TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10910577-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10910577-B2 Organic electroluminescent materials and devices CACNA2D2, ORC3, ANO2 PTPRC 251/4885CTSL 4185/4885CTSS 3843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.