Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.51 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.51 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18822610 | 0.90 | POLB (0.53) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL21132939 | 0.86 | POLB (0.49) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL21133334 | 0.86 | POLB (0.49) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL21133327 | 0.86 | POLB (0.49) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL21133333 | 0.85 | RNASEL (0.58) | POLBP2RY1DNPH1PRKAB2TRPM2 | |
| SCHEMBL20326933 | 0.84 | POLB (0.52) | POLBENPP1P2RY1P2RY2 | |
| SCHEMBL21133335 | 0.84 | POLB (0.47) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL8616900 | 0.84 | P2RY1 (0.66) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL10034046 | 0.82 | POLB (0.66) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL22349189 | 0.82 | POLB (0.51) | POLBENPP1P2RY1DNPH1PRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10906930-B2 | Compositions and methods for activating “stimulator of interferon gene”-dependent signalling | CHINOOK THERAPEUTICS, INC. (US) | 2021-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10906930-B2 | Compositions and methods for activating “stimulator of interferon gene”-dependent signalling | STING1, IRF3, CGAS | POLB 1121/4885ENPP1 653/4885P2RY1 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.