Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | HTT | P42858 | 5/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 3/20 | 0.73 |
| ▸ | MITF | O75030 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | RNF4 | P78317 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | XBP1 | P17861 | 1/20 | 0.59 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.59 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44662 | 0.92 | HTT (0.78) | ALDH1A1HTTNPC1RAB9AMITF | |
| Methane SCHEMBL27966936 | 0.90 | HTT (0.75) | ALDH1A1HTTNPC1RAB9AMITF | |
| Ammonia Solution, Strong SCHEMBL27754901 | 0.90 | HTT (0.75) | ALDH1A1HTTNPC1RAB9AMITF | |
| Ammonia Solution, Strong SCHEMBL27422908 | 0.90 | HTT (0.75) | ALDH1A1HTTNPC1RAB9AMITF | |
| Hydrogen Sulfide SCHEMBL10948577 | 0.90 | HTT (0.75) | ALDH1A1HTTNPC1RAB9AMITF | |
| Iodide SCHEMBL998878 | 0.90 | HTT (0.75) | ALDH1A1HTTNPC1RAB9AMITF | |
| Hydrochloric Acid SCHEMBL9483678 | 0.90 | HTT (0.75) | ALDH1A1HTTNPC1RAB9AMITF | |
| SCHEMBL11655190 | 0.89 | ALDH1A1 (0.73) | ALDH1A1HTTNPC1RAB9AMITF | |
| SCHEMBL9081388 | 0.85 | NPC1 (0.76) | ALDH1A1HTTNPC1RAB9AMITF | |
| SCHEMBL2330263 | 0.85 | ALDH1A1 (1.00) | ALDH1A1HTTNPC1RAB9AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3771687-A1 | REVERSIBLE PHOTO-CONTROLLED FRAC NANOPORES, MODIFIED FRAC MONOMERS, METHODS FOR PREPARING THE SAME, AND USES THEREOF | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2021-02-03 | — | — | EP | disclosed |