Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.61 |
| ▸ | HTR2C | P28335 | 7/20 | 0.61 |
| ▸ | HTR2B | P41595 | 7/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399182 | 0.81 | SLC6A4 (0.48) | HTR2AHTR2CHTR2BSLC6A4KDM4E | |
| SCHEMBL24328229 | 0.80 | SLC6A4 (0.45) | HTR2AHTR2CHTR2BSLC6A4KDM4E | |
| SCHEMBL24243719 | 0.79 | HTR2A (0.50) | HTR2AHTR2CHTR2BSLC6A4HTR1A | |
| SCHEMBL26941658 | 0.79 | NR3C2 (0.46) | HTR2AHTR2CHTR2BSLC6A4MEN1 | |
| SCHEMBL1223582 | 0.78 | GPR84 (0.69) | HTR2AHTR2CHTR2BSLC6A4KDM4E | |
| SCHEMBL8546682 | 0.77 | HTR2A (0.62) | HTR2AHTR2CHTR2BSLC6A4CYP3A4 | |
| SCHEMBL14548391 | 0.77 | NR3C2 (0.44) | HTR2AHTR2CHTR2BSLC6A4MEN1 | |
| SCHEMBL4204578 | 0.76 | HTR2A (0.72) | HTR2AHTR2CHTR2BSLC6A4KDM4E | |
| SCHEMBL1225093 | 0.76 | SLC6A4 (0.68) | HTR2AHTR2CHTR2BSLC6A4KDM4E | |
| SCHEMBL30681654 | 0.76 | HTR2A (1.00) | HTR2AHTR2CHTR2BKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8945397-B2 | Methods of inhibiting cyanobacteria growth by administering gramine derivatives | CYANOTROL, LLC (US) | 2015-02-03 | — | — | US | disclosed |
| US-8945397-B2 | Methods of inhibiting cyanobacteria growth by administering gramine derivatives | CYANOTROL, LLC (US) | 2015-02-03 | — | — | US | disclosed |
| US-8945397-B2 | Methods of inhibiting cyanobacteria growth by administering gramine derivatives | CYANOTROL, LLC (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140110350-A1 | METHODS OF INHIBITING CYANOBACTERIA GROWTH BY ADMINISTERING GRAMINE DERIVATIVES | SAN FRANCISCO STATE UNIVERSITY (US) | 2014-04-24 | — | — | US | disclosed |
| US-20140110350-A1 | METHODS OF INHIBITING CYANOBACTERIA GROWTH BY ADMINISTERING GRAMINE DERIVATIVES | SAN FRANCISCO STATE UNIVERSITY (US) | 2014-04-24 | — | — | US | disclosed |
| US-20140110350-A1 | METHODS OF INHIBITING CYANOBACTERIA GROWTH BY ADMINISTERING GRAMINE DERIVATIVES | SAN FRANCISCO STATE UNIVERSITY (US) | 2014-04-24 | — | — | US | disclosed |
| US-20110201615-A1 | TRIAZOLE BETA CARBOLINE DERIVATIVES AS ANTI-DIABETIC AGENTS | MERCK SHARP & DOHME CORP. | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201615-A1 | TRIAZOLE BETA CARBOLINE DERIVATIVES AS ANTI-DIABETIC AGENTS | GPR119, SSTR3, SSTR2 | HTR2A 63/4885HTR2C 25/4885HTR2B 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.