SCHEMBL2293347

SCHEMBL2293347

CCC(OCC1CO1)C([SiH3])(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5087023 0.85 ALDH1A1 (0.40) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL14776417 0.83 ALDH1A1 (0.35) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL16913022 0.83 ALDH1A1 (0.41) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL16913021 0.81 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2TDP1
SCHEMBL6406979 0.77 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL6153672 0.77 ALDH1A1 (0.41) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL529971 0.76 ALDH1A1 (0.41) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL7218169 0.75 TSHR (0.42) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL3295337 0.72 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL8350594 0.70 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180333347-A1 PHOTOCHEMICALLY STABLE, NON-LEACHING SUNSCREENS FROM EPOXIDE-BASED SILANE COUPLING AGENTS AND UV ABSORBING CHROMOPHORES ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2018-11-22 US claimed
US-8916624-B2 Dental compositions crosslinkable/polymerizable by cationic process BLUESTAR SILICONES FRANCE SAS (FR) 2014-12-23 US claimed
US-20110189632-A1 DENTAL COMPOSITIONS CROSSLINKABLE/POLYMERIZABLE BY CATIONIC PROCESS BLUESTAR SILICONES FRANCE (FR) 2011-08-04 US claimed
US-7740482-B2 Stable cationically crosslinkable/polymerizable dental composition with a high filler content BLUESTAR SILICONES FRANCE (FR) 2010-06-22 US claimed
EP-1745083-B1 HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION BLUESTAR SILICONES FRANCE (FR) 2009-12-16 EP claimed
EP-2043588-B1 DENTAL COMPOSITION CROSSLINKABLE/POLYMERIZABLE BY CATIONIC PROCESS BLUESTAR SILICONES FRANCE (FR) 2009-11-18 EP claimed
US-20080287562-A1 Stable cationically crosslinkable/polymerizable dental composition with a high filler content RHODIA CHIMIE (FR) 2008-11-20 US claimed
EP-1745083-A1 HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION Rhodia Chimie (FR) 2007-01-24 EP claimed
WO-2005121200-A1 HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION RHODIA CHIMIE (FR) 2005-12-22 WO claimed
US-20050261390-A1 Stable cationically crosslinkable/polymerizable dental composition with a high filler content RHODIA CHIMIE (FR) 2005-11-24 US claimed
WO-2025111124-A1 COATED FABRIC ARTICLES DOW SILICONES CORPORATION (US) 2025-05-30 WO disclosed
WO-2025111129-A1 PREPARATION OF SILICONE COMPOSITIONS AND MATERIALS DOW SILICONES CORPORATION (US) 2025-05-30 WO disclosed
WO-2023054701-A1 CURABLE COMPOSITION 株式会社カネカ 2023-04-06 WO disclosed
WO-2023054700-A1 CURABLE COMPOSITION 株式会社カネカ 2023-04-06 WO disclosed
US-20180333347-A1 PHOTOCHEMICALLY STABLE, NON-LEACHING SUNSCREENS FROM EPOXIDE-BASED SILANE COUPLING AGENTS AND UV ABSORBING CHROMOPHORES ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2018-11-22 US disclosed
US-20080287562-A1 Stable cationically crosslinkable/polymerizable dental composition with a high filler content RHODIA CHIMIE (FR) 2008-11-20 US disclosed
WO-2008009718-A2 DENTAL COMPOSITION CROSSLINKABLE/POLYMERIZABLE BY CATIONIC PROCESS BLUESTAR SILICONES FRANCE (FR) 2008-01-24 WO disclosed
EP-1745083-A1 HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION Rhodia Chimie (FR) 2007-01-24 EP disclosed
WO-2005121200-A1 HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION RHODIA CHIMIE (FR) 2005-12-22 WO disclosed
US-20050261390-A1 Stable cationically crosslinkable/polymerizable dental composition with a high filler content RHODIA CHIMIE (FR) 2005-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080287562-A1 Stable cationically crosslinkable/polymerizable dental composition with a high filler content RFC1, RFC2, HNRNPC ALDH1A1 2637/4885TSHR 1372/4885MAPK1 3497/4885
US-20180333347-A1 PHOTOCHEMICALLY STABLE, NON-LEACHING SUNSCREENS FROM EPOXIDE-BASED SILANE COUPLING AGENTS AND UV ABSORBING CHROMOPHORES CCNE2, SUN2, CCNE1 ALDH1A1 173/4885TSHR 4816/4885MAPK1 3310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.