Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2293347 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL16913021 | 0.83 | ALDH1A1 (0.35) | ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL28066742 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL5173144 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TDP1SMN1; SMN2SPHK1TSHR | |
| SCHEMBL37928 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TDP1SMN1; SMN2SPHK1TSHR | |
| SCHEMBL31249514 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TDP1SMN1; SMN2SPHK1TSHR | |
| SCHEMBL22817581 | 0.73 | OPRM1 (0.33) | — | |
| Propylene Oxide SCHEMBL8468510 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TDP1SMN1; SMN2SPHK1TSHR | |
| SCHEMBL17102749 | 0.73 | ALDH1A1 (0.55) | ALDH1A1TDP1SMN1; SMN2SPHK1TSHR | |
| SCHEMBL1931230 | 0.73 | ALDH1A1 (0.55) | ALDH1A1TDP1SMN1; SMN2SPHK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9200146-B2 | Addition-crosslinking silicone composition with low compression set | WACKER CHEMIE AG (DE) | 2015-12-01 | — | — | US | disclosed |
| US-20150203664-A1 | ADDITION-CROSSLINKING SILICONE COMPOSITION WITH LOW COMPRESSION SET | WACKER CHEMIE AG (DE) | 2015-07-23 | — | — | US | disclosed |