SCHEMBL2293435

SCHEMBL2293435

O=C(Nc1ccc2ccccc2c1)[C@@H]1CCCN1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.58
RECQL P46063 1/20 0.58
PSMB8 P28062 2/20 0.56
ULK1 O75385 1/20 0.52
KHK P50053 2/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPT P10636 2/20 0.50
POLB P06746 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TERT O14746 1/20 0.49
EPHX1 P07099 1/20 0.49
SCN3A Q9NY46 2/20 0.48
SCN9A Q15858 2/20 0.48
LMNA P02545 2/20 0.48
HTR1E P28566 1/20 0.48
HTT P42858 1/20 0.48
S1PR3 Q99500 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7187311 1.00 CYP1A2 (0.58) CYP1A2RECQLPSMB8ULK1KHK
SCHEMBL10913060 1.00 CYP1A2 (0.58) CYP1A2RECQLPSMB8ULK1KHK
SCHEMBL29757656 1.00 CYP1A2 (0.58) CYP1A2RECQLPSMB8ULK1KHK
Hydrochloric Acid SCHEMBL28580045 0.99 CYP1A2 (0.56) CYP1A2RECQLPSMB8ULK1KHK
SCHEMBL23373324 0.87 PFKFB3 (0.59) MEN1KMT2AMAPTL3MBTL1LMNA
SCHEMBL3341023 0.82 NPC1 (0.58) CYP1A2PSMB8ULK1MEN1KMT2A
SCHEMBL3343865 0.82 NPC1 (0.58) CYP1A2PSMB8ULK1MEN1KMT2A
SCHEMBL3341031 0.82 NPC1 (0.58) CYP1A2PSMB8ULK1MEN1KMT2A
SCHEMBL2172641 0.82 HPGD (0.56) CYP1A2PSMB8ULK1KHKMEN1
SCHEMBL2392383 0.82 HPGD (0.56) CYP1A2PSMB8ULK1KHKMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050095660-A1 Enzyme activities and pH tests for the determination of the risk of obstetric and gynecologic complications in samples of body fluids of women UNIBIO, S.R.I. (IT) 2005-05-05 US claimed
EP-1528396-A1 Enzyme activities and pH tests for the determination of the risk of obstetric and gynecologic complications in samples of body fluids of women UNIBIO S.R.L. (IT) 2005-05-04 EP claimed
US-20040219617-A1 Enzymatic test for the determination of the risk of pathologies related to the presence of sialidase or prolidase activity in women body fluid samples UNIBIO S.R.L. (IT) 2004-11-04 US claimed
EP-1360484-A1 ENZYMATIC TEST FOR THE DETERMINATION OF THE RISK OF PATHOLOGIES RELATED TO THE PRESENCE OF SIALIDASE OR PROLIDASE ACTIVITY IN WOMEN BODY FLUID SAMPLES UNIBIO S.R.L. (IT) 2003-11-12 EP claimed
WO-2002065122-A1 ENZYMATIC TEST FOR THE DETERMINATION OF THE RISK OF PATHOLOGIES RELATED TO THE PRESENCE OF SIALIDASE OR PROLIDASE ACTIVITY IN WOMEN BODY FLUID SAMPLES UNIBIO S.R.L. (IT) 2002-08-22 WO claimed
US-5571684-A SOLID PHASE CONJUGATE LITMUS CONCEPTS, INC. (US) 1996-11-05 US claimed
US-5116735-A Colorimetric assay, hydrolysis of chromogen THE UNIVERSITY OF MICHIGAN (US) 1992-05-26 US claimed
US-4603108-A Method for identification of bacterial species NATIONAL RESEARCH DEVELOPMENT CORP. (GB) 1986-07-29 US claimed
EP-0018825-B1 A PROCESS FOR THE IDENTIFICATION OF BACTERIA AND A KIT OF REAGENTS FOR USE IN THIS PROCESS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1985-02-13 EP claimed
WO-2023088470-A1 PROBIOTIC COMPOSITIONS FOR TREATMENT OF HAIR LOSS THE CHINESE UNIVERSITY OF HONG KONG (CN) 2023-05-25 WO disclosed
US-20230114304-A1 DEPALMITOYLATING COMPOSITIONS AND THE USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-04-13 US disclosed
EP-4013498-A1 DEPALMITOYLATING COMPOSITIONS AND THE USE THEREOF The Regents of the University of California (US) 2022-06-22 EP disclosed
WO-2021030703-A1 DEPALMITOYLATING COMPOSITIONS AND THE USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-02-18 WO disclosed
US-10760112-B2 Enzymatic activity assays for glucocerebrosidase SHIRE HUMAN GENETIC THERAPIES, INC. (US) 2020-09-01 US disclosed
US-5116735-A Colorimetric assay, hydrolysis of chromogen THE UNIVERSITY OF MICHIGAN (US) 1992-05-26 US disclosed
EP-0255341-A2 Reagent for testing periodontal diseases SUNSTAR KABUSHIKI KAISHA (JP) 1988-02-03 EP disclosed
US-4603108-A Method for identification of bacterial species NATIONAL RESEARCH DEVELOPMENT CORP. (GB) 1986-07-29 US disclosed
EP-0018825-B1 A PROCESS FOR THE IDENTIFICATION OF BACTERIA AND A KIT OF REAGENTS FOR USE IN THIS PROCESS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1985-02-13 EP disclosed
EP-0122028-A1 Colorimetric assay for enzymes, diagnostic article therefor and a method for forming such article E-Y LABORATORIES, INC. (US) 1984-10-17 EP disclosed
EP-0018825-A1 A process for the identification of bacteria and a kit of reagents for use in this process NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1980-11-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230114304-A1 DEPALMITOYLATING COMPOSITIONS AND THE USE THEREOF LIPA, LCAT, SGMS2 CYP1A2 2732/4885RECQL 2019/4885PSMB8 2189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.