SCHEMBL2293652

SCHEMBL2293652

CCC(C(=O)OC(C)(C)C)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
LMNA P02545 2/20 0.55
KDM4E B2RXH2 2/20 0.50
GAA P10253 1/20 0.50
HSD17B10 Q99714 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.47
MAPT P10636 1/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 3/20 0.46
RECQL P46063 1/20 0.46
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2291108 0.87 CTSK (0.44) MEN1KMT2ALMNAGAAL3MBTL1
SCHEMBL28620586 0.86 MEN1 (0.51) MEN1KMT2ALMNAKDM4EGAA
SCHEMBL28246353 0.85 AAK1 (0.42) MEN1KMT2ALMNAGAAL3MBTL1
SCHEMBL27663392 0.85 MAPT (0.45) MEN1KMT2ALMNAGAAL3MBTL1
SCHEMBL27792094 0.85 MEN1 (0.50) MEN1KMT2ALMNAKDM4EGAA
SCHEMBL8011431 0.85 MAPT (0.45) MEN1KMT2ALMNAGAAL3MBTL1
SCHEMBL15268712 0.85 SLC6A2 (0.42) MEN1KMT2ALMNAL3MBTL1
SCHEMBL4610464 0.85 AAK1 (0.42) MEN1KMT2ALMNAKDM4EGAA
SCHEMBL2293825 0.84 CTSK (0.51) POLB
SCHEMBL2022790 0.84 MEN1 (0.50) MEN1KMT2ALMNAKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113278604-A Method for hydrolyzing and splitting 2-phenylbutyric acid enantiomer by using immobilized lipase as catalyst 湖南理工学院 2021-08-20 CN claimed
EP-1490469-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS North Carolina State University (US) 2004-12-29 EP claimed
US-20030213747-A1 Methods and compositions for removing residues and substances from substrates using environmentally friendly solvents NORTH CAROLINA STATE UNIVERSITY 2003-11-20 US claimed
WO-2003072215-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS NORTH CAROLINA STATE UNIVERSITY (US) 2003-09-04 WO claimed
US-11732223-B2 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof Crude Spill Cleaning Co. Inc (US) 2023-08-22 US disclosed
US-11001789-B2 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof Crude Spill Cleaning Co. Inc. (US) 2021-05-11 US disclosed
US-10231960-B2 Methylphenidate-prodrugs, processes of making and using the same KEMPHARM INC. (US) 2019-03-19 US disclosed
US-20180037850-A1 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof CRUDE SPILL CLEANING COMPANY, INC. 2018-02-08 US disclosed
US-20170049765-A1 Methylphenidate-Prodrugs, Processes of Making and Using the Same COMMAVE THERAPEUTICS SA (CH) 2017-02-23 US disclosed
US-20150152363-A1 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof TROXLER ELECTRONIC LABORATORIES, INC. 2015-06-04 US disclosed
US-8951951-B2 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof TROXLER ELECTRONIC LABORATORIES, INC. (US) 2015-02-10 US disclosed
US-8951952-B2 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof TROXLER ELECTRONIC LABORATORIES, INC. (US) 2015-02-10 US disclosed
EP-1723224-A4 SOLVENT COMPOSITIONS FOR REMOVING PETROLEUM RESIDUE FROM A SUBSTRATE AND METHODS OF USE THEREOF TROXLER ELECTRONICS LAB INC (US) 2008-02-27 EP disclosed
US-20070095753-A1 Methods and compositions for removing residues and substances from substrates using environmentally friendly solvents CARBONELL RUBEN G 2007-05-03 US disclosed
EP-1723224-A2 SOLVENT COMPOSITIONS FOR REMOVING PETROLEUM RESIDUE FROM A SUBSTRATE AND METHODS OF USE THEREOF Troxler Electronics Laboratories, Inc. (US) 2006-11-22 EP disclosed
WO-2005091771-A2 SOLVENT COMPOSITIONS FOR REMOVING PETROLEUM RESIDUE FROM A SUBSTRATE AND METHODS OF USE THEREOF TROXLER ELECTRONICS LABORATORIES, INC. (US) 2005-10-06 WO disclosed
US-20050197267-A1 10-60% by weight aromatic ester, 30-60% by weight aliphatic ester, 0-15% by weight co-solvent, 0-10% by weight cyclic terpene or terpenoid, 0-1% by weight odor-masking agent and 0-20% by weight nonionic surfactant; for removing petroleum residues (e.g., asphalt) from work surface such as truck bed TROXLER ELECTRONICS LABORATORIES, INC. (US) 2005-09-08 US disclosed
EP-1490469-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS North Carolina State University (US) 2004-12-29 EP disclosed
US-20030213747-A1 Methods and compositions for removing residues and substances from substrates using environmentally friendly solvents NORTH CAROLINA STATE UNIVERSITY 2003-11-20 US disclosed
WO-2003072215-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS NORTH CAROLINA STATE UNIVERSITY (US) 2003-09-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170049765-A1 Methylphenidate-Prodrugs, Processes of Making and Using the Same COMT, TPMT, PNMT MEN1 2416/4885KMT2A 213/4885LMNA 4533/4885
US-10231960-B2 Methylphenidate-prodrugs, processes of making and using the same COMT, TPMT, PNMT MEN1 2416/4885KMT2A 213/4885LMNA 4533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.