Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171776 | 0.98 | MEN1 (0.56) | APLNRMEN1ALDH1A1KMT2ACNR1 | |
| SCHEMBL30358658 | 0.98 | MEN1 (0.56) | APLNRMEN1ALDH1A1KMT2ACNR1 | |
| Methylamine SCHEMBL27659015 | 0.95 | HTR2A (0.54) | APLNRMEN1ALDH1A1KMT2ACNR1 | |
| SCHEMBL9417780 | 0.95 | APLNR (0.58) | APLNRMEN1ALDH1A1KMT2ACNR1 | |
| SCHEMBL30107392 | 0.89 | APLNR (0.63) | APLNRALDH1A1HTR2A | |
| SCHEMBL6123805 | 0.87 | APLNR (0.61) | APLNRALDH1A1CNR1ALOX5HTR2A | |
| SCHEMBL9889155 | 0.86 | ADRA1A (0.64) | ALOX5HTR2APTGS2 | |
| SCHEMBL18641701 | 0.85 | ESR1 (0.46) | MEN1ALDH1A1KMT2ATSHRALOX5 | |
| SCHEMBL10767997 | 0.84 | ADRA1A (0.62) | ALOX5HTR2APTGS2 | |
| SCHEMBL10601156 | 0.84 | ADRA1A (0.62) | ALOX5HTR2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021904-A1 | PHARMACOLOGICAL INHIBITORS OF THE ENL YEATS DOMAIN | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-02-04 | — | — | WO | disclosed |