Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22943931 | 1.00 | HRH3 (0.47) | HRH3KCNH2CCR2IRAK4PDK1 | |
| SCHEMBL22944238 | 1.00 | HRH3 (0.47) | HRH3KCNH2CCR2IRAK4PDK1 | |
| SCHEMBL23710030 | 0.91 | HRH3 (0.47) | HRH3KCNH2CCR2HTR4 | |
| SCHEMBL7778115 | 0.91 | HRH3 (0.53) | HRH3HTR4 | |
| SCHEMBL23487053 | 0.85 | HRH3 (0.39) | HRH3PDK1 | |
| SCHEMBL22320479 | 0.80 | PDK1 (0.49) | HRH3KCNH2CCR2IRAK4PDK1 | |
| SCHEMBL22320480 | 0.80 | PDK1 (0.49) | HRH3KCNH2CCR2IRAK4PDK1 | |
| SCHEMBL25001882 | 0.76 | HRH3 (0.41) | HRH3KCNH2CCR2HTR4 | |
| SCHEMBL4403337 | 0.76 | ERBB2 (0.34) | HRH3 | |
| SCHEMBL24774772 | 0.75 | HRH3 (0.39) | HRH3KCNH2CCR2IRAK4HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021019514-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | INTEGRAL BIOSCIENCES PVT. LTD. (IN) | 2021-02-04 | — | — | WO | disclosed |