Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22943931 | 0.91 | HRH3 (0.47) | HRH3HTR4KCNH2CCR2 | |
| SCHEMBL22944237 | 0.91 | HRH3 (0.47) | HRH3HTR4KCNH2CCR2 | |
| SCHEMBL22944238 | 0.91 | HRH3 (0.47) | HRH3HTR4KCNH2CCR2 | |
| SCHEMBL7778115 | 0.86 | HRH3 (0.53) | HRH3HTR4EPHA2KDR | |
| SCHEMBL23487053 | 0.84 | HRH3 (0.39) | HRH3 | |
| SCHEMBL22732611 | 0.82 | HRH3 (0.42) | HRH3HTR4EPHA2KDRALDH1A1 | |
| SCHEMBL22732727 | 0.82 | HRH3 (0.42) | HRH3HTR4EPHA2KDRALDH1A1 | |
| SCHEMBL22732893 | 0.81 | HTR4 (0.43) | HRH3HTR4EPHA2KDRALDH1A1 | |
| Hydrochloric Acid SCHEMBL30133730 | 0.81 | HRH3 (0.41) | HRH3HTR4EPHA2KDRALDH1A1 | |
| SCHEMBL24171111 | 0.78 | HTR4 (0.43) | HRH3HTR4EPHA2KDRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858832-A1 | TRIFLUOROMETHYL-SUBSTITUTED SULFONAMIDE AS BCL-2-SELECTIVE INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |