SCHEMBL22945160

SCHEMBL22945160

c1cc(-c2nc(-c3ccc4sc5ccccc5c4c3)c3ccccc3n2)cc(N2c3cc4ccccc4cc3-c3cccc4cccc2c34)c1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ATM Q13315 1/20 0.34
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
DUSP3 P51452 1/20 0.33
PTPN5 P54829 1/20 0.33
PTPN11 Q06124 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
PDK1 Q15118 1/20 0.30
PDK2 Q15119 1/20 0.30
PDK3 Q15120 1/20 0.30
PDK4 Q16654 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21515437 0.94 PDE6D (0.36) PDE6DMEN1KMT2AATMKDM4E
SCHEMBL22946082 0.88 PDE6D (0.31) PDE6D
SCHEMBL22945496 0.87 ALDH1A1 (0.33) PDE6DKMT2AATMKDM4EPOLB
SCHEMBL22945162 0.85 PDE6D (0.32) PDE6DMEN1KMT2AATM
SCHEMBL22944801 0.84 PDE6D (0.37) PDE6D
SCHEMBL26737197 0.83 PDE6D (0.37) PDE6D
SCHEMBL22945054 0.82 PDE6D (0.34) PDE6DPOLB
SCHEMBL21515460 0.82 MEN1 (0.35) PDE6DMEN1KMT2AATMKDM4E
SCHEMBL22945498 0.82 ALDH1A1 (0.33) PDE6DKMT2AATMKDM4EPOLB
SCHEMBL22945640 0.82 PDE6D (0.35) PDE6DPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME DRD1, DRD3, DRD2 PDE6D 342/4885MEN1 1827/4885KMT2A 1519/4885
US-11812658-B2 Compound and organic light emitting diode comprising same DRD1, DRD3, DRD2 PDE6D 342/4885MEN1 1827/4885KMT2A 1519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.