SCHEMBL22945180

SCHEMBL22945180

c1ccc2cc(-c3nc(-c4ccc5sc6ccccc6c5c4)nc(N4c5ccc6ccccc6c5-c5cccc6cccc4c56)n3)ccc2c1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
S1PR5 Q9H228 4/20 0.32
S1PR4 O95977 3/20 0.32
PDE6D O43924 1/20 0.31
POLB P06746 1/20 0.30
PIM1 P11309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22944695 0.97 PDE6D (0.33) PDE6DPOLB
SCHEMBL22945527 0.94 PDE6D (0.35) PDE6DPOLB
SCHEMBL22945416 0.94 PDE6D (0.31) PDE6DPOLB
SCHEMBL22945418 0.93 PDE6D (0.30) PDE6D
SCHEMBL22945217 0.92 ALOX5 (0.36)
SCHEMBL22945209 0.90 S1PR5 (0.34) S1PR5S1PR4PDE6DPOLB
SCHEMBL22945242 0.90
SCHEMBL22944705 0.89
SCHEMBL22945955 0.89 PDE6D (0.35) PDE6DPOLB
SCHEMBL22945488 0.88 S1PR5 (0.33) S1PR5S1PR4PDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME DRD1, DRD3, DRD2 S1PR5 3443/4885S1PR4 3775/4885PDE6D 342/4885
US-11812658-B2 Compound and organic light emitting diode comprising same DRD1, DRD3, DRD2 S1PR5 3443/4885S1PR4 3775/4885PDE6D 342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.