Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | ALB | P02768 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | STING1 | Q86WV6 | 7/20 | 0.45 |
| ▸ | TYMP | P19971 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2294538 | 0.84 | ALDH1A1 (0.68) | ALDH1A1LMNAALBMAPK1STING1 | |
| SCHEMBL10015783 | 0.84 | ALDH1A1 (0.68) | ALDH1A1LMNAALBMAPK1STING1 | |
| SCHEMBL24358288 | 0.82 | ALDH1A1 (0.80) | ALDH1A1LMNAALBMAPK1STING1 | |
| SCHEMBL9548834 | 0.82 | ALDH1A1 (0.65) | ALDH1A1LMNAALBMAPK1STING1 | |
| Didanosine SCHEMBL16695885 | 0.81 | ALDH1A1 (1.00) | ALDH1A1LMNAALBMAPK1STING1 | |
| SCHEMBL21637037 | 0.81 | ALDH1A1 (0.78) | ALDH1A1LMNAALBMAPK1STING1 | |
| Didanosine SCHEMBL16695883 | 0.81 | ALDH1A1 (1.00) | ALDH1A1LMNAALBMAPK1STING1 | |
| SCHEMBL13769966 | 0.81 | ALDH1A1 (0.78) | ALDH1A1LMNAALBMAPK1STING1 | |
| Didanosine SCHEMBL5021456 | 0.81 | ALDH1A1 (1.00) | ALDH1A1LMNAALBMAPK1STING1 | |
| Didanosine SCHEMBL1674335 | 0.81 | ALDH1A1 (1.00) | ALDH1A1LMNAALBMAPK1STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2055711-B1 | Use of squalenic acid for the formulation of an active principle in nanoparticle state | CENTRE NAT RECH SCIENT (FR) | 2011-08-17 | — | — | EP | disclosed |
| EP-2055711-A1 | Use of squalenic acid for the formulation of an active principle in nanoparticle state | Centre National de la Recherche Scientifique (FR) | 2009-05-06 | — | — | EP | disclosed |
| EP-1925624-A1 | Use of squalenic acid for the formulation of an active principle in nanoparticle state | Centre National de la Recherche Scientifique (FR) | 2008-05-28 | — | — | EP | disclosed |
| EP-1761551-A1 | GEMCITABINE DERIVATIVES NANOPARTICLES | The Centre National de la Recherche Scientifique (FR) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006090029-A1 | GEMCITABINE DERIVATIVES NANOPARTICLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2006-08-31 | — | — | WO | disclosed |