Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | ALB | P02768 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | TYMP | P19971 | 4/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 6/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2294535 | 0.82 | ALDH1A1 (0.68) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL2294538 | 0.82 | ALDH1A1 (0.68) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL10015783 | 0.82 | ALDH1A1 (0.68) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL9548681 | 0.82 | POLB (0.48) | ALDH1A1LMNAALBMAPK1STING1 | |
| SCHEMBL21637037 | 0.81 | ALDH1A1 (0.78) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL24358288 | 0.80 | ALDH1A1 (0.80) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL13769966 | 0.79 | ALDH1A1 (0.78) | ALDH1A1LMNAALBMAPK1TYMP | |
| Didanosine SCHEMBL1674335 | 0.79 | ALDH1A1 (1.00) | ALDH1A1LMNAALBMAPK1TYMP | |
| Didanosine SCHEMBL16695885 | 0.79 | ALDH1A1 (1.00) | ALDH1A1LMNAALBMAPK1TYMP | |
| Didanosine SCHEMBL5021456 | 0.79 | ALDH1A1 (1.00) | ALDH1A1LMNAALBMAPK1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192749-A | Viricide, AIDS | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |