SCHEMBL22945443

SCHEMBL22945443

c1ccc2c3c(ccc2c1)N(c1nc(-c2ccc4c(c2)sc2ccccc24)c2sc4ccccc4c2n1)c1cccc2cccc-3c12

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.31
PRKDC P78527 1/20 0.31
LIMK1 P53667 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22945442 0.95 ALOX5 (0.31) ALOX5
SCHEMBL22944781 0.93 S1PR4 (0.31) ALOX5
SCHEMBL22945981 0.90 PDE6D (0.37)
SCHEMBL22944782 0.90 MEN1 (0.36) LIMK1
SCHEMBL22945233 0.90 ALOX5 (0.34) ALOX5PRKDCLIMK1
SCHEMBL22945279 0.89 PDE6D (0.31)
SCHEMBL22945558 0.89 PRKDC (0.35) PRKDC
SCHEMBL22946023 0.88 ALOX5 (0.32) ALOX5PRKDCLIMK1
SCHEMBL22945441 0.88 ALOX5 (0.32) ALOX5PRKDC
SCHEMBL22945278 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME DRD1, DRD3, DRD2 ALOX5 386/4885PRKDC 4810/4885LIMK1 913/4885
US-11812658-B2 Compound and organic light emitting diode comprising same DRD1, DRD3, DRD2 ALOX5 386/4885PRKDC 4810/4885LIMK1 913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.