SCHEMBL22945687

SCHEMBL22945687

c1ccc2cc3c(cc2c1)-c1cccc2cccc(c12)N3c1ccc(-c2nc(-c3cccc4cccnc34)c3ccccc3n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.39
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ATM Q13315 1/20 0.34
POLB P06746 2/20 0.33
PSMD14 O00487 1/20 0.33
TP53 P04637 1/20 0.33
MMP2 P08253 1/20 0.33
PDE10A Q9Y233 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
ALDH1A1 P00352 1/20 0.31
AHR P35869 1/20 0.31
ATR Q13535 1/20 0.31
MMP9 P14780 1/20 0.30
TOP1 P11387 2/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21515453 0.92 PDE6D (0.41) PDE6DMEN1KMT2AATMPOLB
SCHEMBL22945340 0.89 PDE6D (0.40) PDE6DMEN1KMT2AATMPOLB
SCHEMBL22945339 0.86 PDE10A (0.36) PDE6DMEN1KMT2APOLBPSMD14
SCHEMBL22945145 0.86 PDE6D (0.38) PDE6DMEN1KMT2AATMPOLB
SCHEMBL22945685 0.86 MMP9 (0.33) PDE6DMEN1KMT2AATMPDE10A
SCHEMBL22945686 0.86 PDE6D (0.38) PDE6DMEN1KMT2AATMPOLB
SCHEMBL22946044 0.85 HPGD (0.42) PDE6DMEN1KMT2AATMPOLB
SCHEMBL22945937 0.84 PDE6D (0.33) PDE6DMEN1KMT2APOLBCYP1A2
SCHEMBL22945514 0.84 PDE6D (0.33) PDE6DMEN1KMT2APOLBPSMD14
SCHEMBL22945336 0.83 HPGD (0.36) PDE6DKMT2AATMPOLBPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME DRD1, DRD3, DRD2 PDE6D 342/4885MEN1 1827/4885KMT2A 1519/4885
US-11812658-B2 Compound and organic light emitting diode comprising same DRD1, DRD3, DRD2 PDE6D 342/4885MEN1 1827/4885KMT2A 1519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.