Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22946170 | 0.85 | ALDH1A1 (0.40) | MAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL22945854 | 0.85 | ALDH1A1 (0.34) | MAPTNPC1RAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL22946204 | 0.83 | ABCB1 (0.43) | MAPTNPC1RAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL8570570 | 0.82 | KDM4E (0.43) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL22945856 | 0.79 | TSHR (0.32) | MAPTNPC1RAB9AHSD11B1CYP1A2 | |
| SCHEMBL22945925 | 0.76 | CNR1 (0.33) | MAPTSMN1; SMN2LMNAALDH1A1NR3C1 | |
| SCHEMBL22946175 | 0.75 | ABCB1 (0.35) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL12555712 | 0.73 | SMN1; SMN2 (0.32) | MAPTNPC1RAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL10961245 | 0.73 | ALKBH1 (0.41) | MAPTSMN1; SMN2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL23061286 | 0.72 | ABCB1 (0.43) | MAPTSMN1; SMN2LMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018135-A1 | HETEROCYCLYL ALKYL SUBSTITUTED DICHLOROBENZOYL COMPOUNDS AND APPLICATIONS THEREOF | 东莞市东阳光农药研发有限公司 | 2021-02-04 | — | — | WO | disclosed |