Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22946159 | 0.87 | GAA (0.35) | ALDH1A1NPC1RORCRAB9A | |
| SCHEMBL22946153 | 0.87 | RORC (0.43) | KMT2AMEN1ALDH1A1NPC1RORC | |
| SCHEMBL22945928 | 0.81 | CNR1 (0.36) | KMT2AMEN1ALDH1A1NPC1RORC | |
| SCHEMBL22945899 | 0.81 | KMT2A (0.37) | KMT2AMEN1ALDH1A1NPC1RORC | |
| SCHEMBL22945894 | 0.81 | ABCB1 (0.38) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL22946323 | 0.81 | KDM4E (0.40) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL22945901 | 0.81 | MEN1 (0.38) | KMT2AMEN1DHODH | |
| SCHEMBL28536613 | 0.77 | RORC (0.35) | KMT2AMEN1ALDH1A1RORCKDM4E | |
| SCHEMBL10680900 | 0.76 | MAPT (0.36) | KMT2AMEN1ALDH1A1RAB9AKDM4E | |
| SCHEMBL23061052 | 0.76 | GPBAR1 (0.36) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018135-A1 | HETEROCYCLYL ALKYL SUBSTITUTED DICHLOROBENZOYL COMPOUNDS AND APPLICATIONS THEREOF | 东莞市东阳光农药研发有限公司 | 2021-02-04 | — | — | WO | disclosed |