Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22946182 | 0.89 | ALDH1A1 (0.39) | ABCB1ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL22946183 | 0.89 | ABCB1 (0.39) | ABCB1ALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL22945890 | 0.89 | HSD11B1 (0.31) | HSD11B1KMT2ACYP1A2CYP2C19NR3C1 | |
| SCHEMBL22946204 | 0.85 | ABCB1 (0.43) | ABCB1ALDH1A1SMN1; SMN2LMNAHSD11B1 | |
| SCHEMBL22945895 | 0.83 | MEN1 (0.35) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL22946180 | 0.82 | HPGD (0.32) | ABCB1ALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL22945896 | 0.82 | CNR1 (0.31) | — | |
| SCHEMBL8466623 | 0.82 | ABCB1 (0.45) | ABCB1ALDH1A1SMN1; SMN2LMNAHSD11B1 | |
| SCHEMBL22945898 | 0.81 | KMT2A (0.38) | ALDH1A1KMT2ACYP1A2CYP2C19MAPT | |
| SCHEMBL22945901 | 0.81 | MEN1 (0.38) | ABCB1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018135-A1 | HETEROCYCLYL ALKYL SUBSTITUTED DICHLOROBENZOYL COMPOUNDS AND APPLICATIONS THEREOF | 东莞市东阳光农药研发有限公司 | 2021-02-04 | — | — | WO | disclosed |