Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15633799 | 0.83 | ADORA3 (0.50) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL8306794 | 0.82 | ADORA3 (0.49) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL20699834 | 0.78 | PI4KA (0.62) | ADORA3ADORA2AADORA1 | |
| SCHEMBL12379237 | 0.78 | PI4KA (0.62) | ADORA3ADORA2AADORA1 | |
| SCHEMBL18571809 | 0.78 | PI4KA (0.62) | ADORA3ADORA2AADORA1 | |
| SCHEMBL23635185 | 0.78 | ADORA3 (0.42) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL118827 | 0.78 | ADORA3 (0.69) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5786575 | 0.77 | ADORA2A (0.48) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL121441 | 0.77 | ADORA3 (0.69) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL1078828 | 0.77 | ADORA2A (0.64) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080293666-A1 | Antibacterial Agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293666-A1 | Antibacterial Agents | MRPL21, ABCB7, MSR1 | ADORA3 1669/4885ADORA2A 2428/4885ADORA1 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.