Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15633799 | 0.90 | ADORA3 (0.50) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5987749 | 0.86 | ADORA2A (0.47) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL118827 | 0.85 | ADORA3 (0.69) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5786575 | 0.84 | ADORA2A (0.48) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL121441 | 0.84 | ADORA3 (0.69) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL1078828 | 0.84 | ADORA2A (0.64) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL2294592 | 0.82 | ADORA3 (0.43) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL122980 | 0.80 | ADORA1 (0.72) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL6870926 | 0.79 | ADORA3 (0.44) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL21480369 | 0.77 | ADORA3 (0.58) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912520-A4 | COMPOUNDS HAVING ANTIHYPERTENSIVE, CARDIOPROTECTIVE, ANTI-ISCHEMIC AND ANTILIPOLYTIC PROPERTIES | RHONE POULENC RORER PHARMA (US) | 1999-10-06 | — | — | EP | disclosed |
| EP-0912520-A1 | COMPOUNDS HAVING ANTIHYPERTENSIVE, CARDIOPROTECTIVE, ANTI-ISCHEMIC AND ANTILIPOLYTIC PROPERTIES | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998001426-A1 | COMPOUNDS HAVING ANTIHYPERTENSIVE, CARDIOPROTECTIVE, ANTI-ISCHEMIC AND ANTILIPOLYTIC PROPERTIES | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-01-15 | — | — | WO | disclosed |