SCHEMBL22945941

SCHEMBL22945941

c1ccc2cc3c(cc2c1)-c1cccc2cccc(c12)N3c1cc(-c2nc(-c3ccc(-c4cccc5cccnc45)cc3)c3oc4ccccc4c3n2)c2ccccc2c1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22945573 0.94 GRM4 (0.33) GRM4
SCHEMBL22945230 0.89 KDM4E (0.31) GRM4
SCHEMBL22945034 0.89 KDM4E (0.31)
SCHEMBL22945937 0.87 PDE6D (0.33) GRM4
SCHEMBL22944919 0.87 TSHR (0.32) GRM4
SCHEMBL22945938 0.82 PDE6D (0.33) GRM4
SCHEMBL22945314 0.81 ALOX5 (0.34)
SCHEMBL22945185 0.81 MAPK9 (0.32)
SCHEMBL22945570 0.80 PDE6D (0.35) GRM4
SCHEMBL22945923 0.80 TSHR (0.34) GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME DRD1, DRD3, DRD2 GRM4 2678/4885
US-11812658-B2 Compound and organic light emitting diode comprising same DRD1, DRD3, DRD2 GRM4 2678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.