Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 14/20 | 0.56 |
| ▸ | LPL | P06858 | 13/20 | 0.56 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31040332 | 1.00 | LIPG (0.56) | LIPGLPLDGAT1P4HBPDGFRB | |
| SCHEMBL22947677 | 0.92 | LIPG (0.49) | LIPGLPLDGAT1P4HBPDGFRB | |
| SCHEMBL22947711 | 0.90 | LIPG (0.51) | LIPGLPLDGAT1P4HBPDGFRB | |
| SCHEMBL11978736 | 0.90 | LIPG (0.46) | LIPGLPLDGAT1P4HBCA1 | |
| SCHEMBL22947651 | 0.88 | LIPG (0.64) | LIPGLPLDGAT1P4HBPDGFRB | |
| SCHEMBL22949269 | 0.86 | LIPG (0.55) | LIPGLPLDGAT1P4HBPDGFRB | |
| SCHEMBL22947498 | 0.85 | LIPG (0.39) | LIPGLPLDGAT1 | |
| SCHEMBL22949401 | 0.84 | LIPG (0.46) | LIPGLPLDGAT1P4HBPDGFRB | |
| SCHEMBL31040334 | 0.84 | LIPG (0.46) | LIPGLPLDGAT1P4HBPDGFRB | |
| SCHEMBL22947706 | 0.83 | LIPG (0.54) | LIPGLPLDGAT1P4HBSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | ETV6, FES, LEF1 | LIPG 2970/4885LPL 4404/4885DGAT1 3563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.