Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22947441 | 0.91 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL22961173 | 0.90 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2APTPRCKDM4E | |
| SCHEMBL11984775 | 0.88 | PTPRC (0.40) | ALDH1A1PTPRCMAPK1CA12CA9 | |
| SCHEMBL17451613 | 0.86 | CA12 (0.41) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL21123265 | 0.82 | PTPRC (0.39) | ALDH1A1PTPRCMAPK1CA9MAPT | |
| SCHEMBL19010951 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL22947536 | 0.79 | CYP2A6 (0.50) | ALDH1A1MEN1KMT2APTPRCKDM4E | |
| SCHEMBL26017216 | 0.77 | PTPRC (0.40) | ALDH1A1PTPRCMAPK1CA12CA9 | |
| SCHEMBL22947482 | 0.77 | TNKS2 (0.38) | ALDH1A1MEN1KMT2AMAOBCA12 | |
| SCHEMBL22947628 | 0.77 | PDK2 (0.36) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | ETV6, FES, LEF1 | ALDH1A1 752/4885MEN1 2439/4885KMT2A 2115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.