Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22947556 | 0.90 | MEN1 (0.40) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22947514 | 0.90 | MEN1 (0.40) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22947646 | 0.89 | MEN1 (0.40) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22947695 | 0.89 | MEN1 (0.40) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22947522 | 0.89 | MEN1 (0.39) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22949299 | 0.89 | MEN1 (0.39) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22949598 | 0.86 | MEN1 (0.37) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22947525 | 0.85 | ADORA3 (0.39) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22947637 | 0.84 | ADORA3 (0.38) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22949337 | 0.84 | MEN1 (0.43) | L3MBTL1MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | ETV6, FES, LEF1 | L3MBTL1 3138/4885MEN1 2439/4885KMT2A 2115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.