Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 1.00 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.68 |
| ▸ | PDE5A | O76074 | 6/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | PDE4A | P27815 | 1/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655570 | 0.87 | MIF (0.78) | MIFPDE4BPDE5APDE3AALDH1A1 | |
| SCHEMBL3192726 | 0.86 | MIF (0.76) | MIFPDE4BPDE5APDE3AALDH1A1 | |
| SCHEMBL7509505 | 0.86 | MIF (0.76) | MIFPDE4BPDE5APDE3AALDH1A1 | |
| SCHEMBL3185498 | 0.86 | MIF (0.76) | MIFPDE4BPDE5APDE3AALDH1A1 | |
| SCHEMBL4340673 | 0.85 | MIF (0.74) | MIFPDE4BPDE5APDE3AALDH1A1 | |
| SCHEMBL2709876 | 0.85 | MIF (0.74) | MIFPDE4BPDE5APDE3AALDH1A1 | |
| SCHEMBL7513484 | 0.84 | MIF (0.72) | MIFPDE4BPDE5APDE3AALDH1A1 | |
| SCHEMBL7508100 | 0.84 | MIF (0.72) | MIFPDE4BPDE5APDE3AALDH1A1 | |
| SCHEMBL3197152 | 0.82 | PDE4B (0.76) | MIFPDE4BPDE5APDE3AALDH1A1 | |
| SCHEMBL653503 | 0.82 | PDE4B (0.76) | MIFPDE4BPDE5APDE3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230033021-A1 | TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN INTEGRIN INHIBITOR | GLAS USA LLC | 2023-02-02 | — | — | US | disclosed |
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | NEURALEXO, INC. | 2022-12-15 | — | — | US | disclosed |
| US-20210031012-A1 | TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A PDE4 INHIBITOR | GLAS USA LLC | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210031012-A1 | TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A PDE4 INHIBITOR | PDE4A, PDE12, PDE4B | MIF 3877/4885PDE4B 3/4885PDE5A 7/4885 |
| US-20230033021-A1 | TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN INTEGRIN INHIBITOR | ITGAL, ITGB2, ITGB1 | MIF 742/4885PDE4B 2437/4885PDE5A 1478/4885 |
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | IRF3, IRF2BP2, STAT1 | MIF 110/4885PDE4B 633/4885PDE5A 1172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.