SCHEMBL229478

SCHEMBL229478

N=C(N)NOP(=O)(O)OP(=O)(O)O

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.39
BLM P54132 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA4 P22748 1/20 0.32
BTN3A1 O00481 2/20 0.31
MVD P53602 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122713 0.96 FDPS (0.36) FDPSBLMTDP1CA4
SCHEMBL4948771 0.85 CA4 (0.32) CA4
SCHEMBL27438 0.80
SCHEMBL4147806 0.79 FDPS (0.41) FDPSBLMTDP1CA4BTN3A1
SCHEMBL7743009 0.79
SCHEMBL11663057 0.78 CA4 (0.42) FDPSBLMTDP1CA4
Phosphine SCHEMBL5594612 0.78 CA4 (0.36) FDPSBLMTDP1CA4
Hydrochloric Acid SCHEMBL1803055 0.78 CA4 (0.36) FDPSBLMTDP1CA4
SCHEMBL17061103 0.78 CA4 (0.36) FDPSBLMTDP1CA4
Triphosphate SCHEMBL8023890 0.78 FDPS (0.50) FDPSBLMTDP1CA4BTN3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080029126-A1 Compositions and methods for improved planarization of copper utilizing inorganic oxide abrasive ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. 2008-02-07 US claimed
US-6971945-B2 Multi-step polishing solution for chemical mechanical planarization ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. (US) 2005-12-06 US claimed
US-20050194357-A1 MULTI-STEP POLISHING SOLUTION FOR CHEMICAL MECHANICAL PLANARIZATION ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. 2005-09-08 US claimed
EP-1548076-A1 Compositions and methods for low downforce pressure polishing of copper Rohm and Haas Electronic Materials CMP Holdings, Inc. (US) 2005-06-29 EP claimed
US-20050136671-A1 Compositions and methods for low downforce pressure polishing of copper ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. 2005-06-23 US claimed
US-12505900-B2 Integrated synthesis and analysis systems and methods of use thereof PURDUE RESEARCH FOUNDATION (US) 2025-12-23 US disclosed
US-12391929-B2 Polymerase-nucleotide conjugates for sequencing by trapping ELEMENT BIOSCIENCES, INC. (US) 2025-08-19 US disclosed
WO-2025074271-A1 MYT1 INHIBITORS FOR THE TREATMENT OF CANCERS HARBORING REPLICATION STRESS MUTATIONS REPARE THERAPEUTICS INC. (CA) 2025-04-10 WO disclosed
US-20240168030-A1 DIRECT FLUORESCENT GLYCAN LABELING BIO TECHNE CORP (US) 2024-05-23 US disclosed
CN-116731147-A Method for preparing fucosylated and defucosylated forms of proteins 豪夫迈·罗氏有限公司 2023-09-12 CN disclosed
US-11723983-B2 Conjugates of a glycoprotein or a glycan with a toxic payload GLYKOS FINLAND OY (FI) 2023-08-15 US disclosed
US-20230187018-A1 INTEGRATED SYNTHESIS AND ANALYSIS SYSTEMS AND METHODS OF USE THEREOF PURDUE RESEARCH FOUNDATION (US) 2023-06-15 US disclosed
EP-0370205-B1 Glycosylated polypeptides KYOWA HAKKO KOGYO KK (JP) 1998-07-22 EP disclosed
EP-0458901-B1 INHIBITING TRANSFORMATION OF CELLS HAVING ELEVATED PURINE METABOLIC ENZYME ACTIVITY MASSACHUSETTS INST TECHNOLOGY (US) 1997-12-17 EP disclosed
EP-0758681-A2 Inhibiting transformation of cells having elevated purine metabolic enzyme activity MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1997-02-19 EP disclosed
US-5218092-A Stability KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-06-08 US disclosed
EP-0509540-A1 Dye-fixing element FUJI PHOTO FILM CO., LTD. (JP) 1992-10-21 EP disclosed
EP-0458901-A1 INHIBITING TRANSFORMATION OF CELLS HAVING ELEVATED PURINE METABOLIC ENZYME ACTIVITY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1991-12-04 EP disclosed
WO-1990009192-A1 INHIBITING TRANSFORMATION OF CELLS HAVING ELEVATED PURINE METABOLIC ENZYME ACTIVITY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1990-08-23 WO disclosed
EP-0370205-A2 Glycosylated polypeptides KYOWA HAKKO KOGYO CO., LTD. (JP) 1990-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11723983-B2 Conjugates of a glycoprotein or a glycan with a toxic payload FUT6, CD44, SIGLEC7 FDPS 3536/4885BLM 3372/4885TDP1 1571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.