SCHEMBL2294837

SCHEMBL2294837

CC(=O)Nc1nnn[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12057465 0.82 MDM2 (0.33)
SCHEMBL10652900 0.80
SCHEMBL10380209 0.79 ALDH1A1 (0.36)
SCHEMBL1480730 0.79 KDM4E (0.39)
SCHEMBL3991499 0.78
SCHEMBL1260050 0.78
SCHEMBL10175725 0.78 MAPT (0.46)
SCHEMBL4310051 0.78
SCHEMBL10379723 0.78 ROCK2 (0.36)
SCHEMBL12983269 0.78 ALDH1A1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3686207-B1 TETRAZOLE SILANE COMPOUND, METHOD FOR SYNTHESIZING SAID COMPOUND AND USE THEREOF SHIKOKU CHEM (JP) 2024-10-23 EP claimed
CN-117535028-A Expansion type flame-retardant fireproof adhesive and preparation method thereof 四川三棵树涂料有限公司 2024-02-09 CN claimed
US-20090291921-A1 INTEGRASE INHIBITORS GILEAD SCIENCES, INC. (US) 2009-11-26 US claimed
WO-2009067541-A2 INTEGRASE INHIBITORS GILEAD SCIENCES, INC. (US) 2009-05-28 WO claimed
EP-1054669-B9 USE OF THIADIAZOLO[4,3-A]PYRIDINE DERIVATIVES ROCHE DIAGNOSTICS GMBH (DE) 2004-09-15 EP claimed
EP-1054669-B1 USE OF THIADIAZOLO[4,3-A]PYRIDINE DERIVATIVES ROCHE DIAGNOSTICS GMBH (DE) 2003-07-16 EP claimed
US-6326378-B1 LEUKEMIA THERAPY ROCHE DIAGNOSTICS GMBH (DE) 2001-12-04 US claimed
EP-1054669-A2 USE OF THIADIAZOLO[4,3-A]PYRIDINE DERIVATIVES BOEHRINGER MANNHEIM GMBH (DE) 2000-11-29 EP claimed
WO-1999042089-A9 USE OF THIADIAZOLO[4,3-A]PYRIDINE DERIVATIVES ROCHE DIAGNOSTICS GMBH (DE) 1999-10-28 WO claimed
WO-1999042089-A2 USE OF THIADIAZOLO[4,3-A]PYRIDINE DERIVATIVES ROCHE DIAGNOSTICS GMBH (DE) 1999-08-26 WO claimed
US-5447934-A Anti-allergic thiadiazolo [4,3-a]pyridine derivatives BOEHRINGER MANNHEIM GMBH (DE) 1995-09-05 US claimed
JP-9124619-A None JP disclosed
JP-59001472-A None JP disclosed
CN-115066474-B Adhesive composition, adhesive tape, and method for treating electronic component 积水化学工业株式会社 2025-01-03 CN disclosed
WO-2024247919-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF 四国化成工業株式会社 2024-12-05 WO disclosed
US-4544549-A ANTIBIOTICS, BETA-LACTAMASE INHIBITORS BEECHAM GROUP P.L.C. (GB) 1985-10-01 US disclosed
EP-0053893-B1 DERIVATIVES OF CLAVULANIC ACID, THEIR PREPARATION AND THEIR USE BEECHAM GROUP PLC (GB) 1985-03-20 EP disclosed
EP-0107859-A1 Tetrazole compounds, process for preparing the same and antibacterial and antifungal compositions containing the same as active ingredient MEIJI SEIKA KAISHA LTD. (JP) 1984-05-09 EP disclosed
JP-S591472-A TRIIODOALLYL COMPOUND, PREPARATION AND ANTIMICROBIAL AND ANTIFUNGAL AGENT CONTAINING THE SAME AS ACTIVE CONSTITUENT MEIJI SEIKA KAISHA LTD 1984-01-06 JP disclosed
EP-0080051-A2 Heterocyclic compounds and antibacterial and antifungal compositions containing the same as active ingredients MEIJI SEIKA KAISHA LTD. (JP) 1983-06-01 EP disclosed