SCHEMBL2294952

SCHEMBL2294952

Nc1ccccc1C(=O)NS(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
HSD17B10 Q99714 2/20 0.48
CFTR P13569 1/20 0.48
NPC1 O15118 4/20 0.47
RAB9A P51151 4/20 0.47
GAA P10253 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
KDM4E B2RXH2 7/20 0.47
FADS1 O60427 2/20 0.47
MAPT P10636 2/20 0.46
HPGD P15428 3/20 0.45
PTGS1 P23219 1/20 0.45
P2RX1 P51575 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
ACP1 P24666 1/20 0.43
POLB P06746 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10636104 0.85 ALDH1A1 (0.49) ALDH1A1HSD17B10CFTRNPC1RAB9A
SCHEMBL4202292 0.83 MYC (0.55) ALDH1A1HSD17B10CFTRNPC1RAB9A
SCHEMBL18425946 0.81 MAPT (0.48) ALDH1A1HSD17B10CFTRNPC1RAB9A
SCHEMBL4196234 0.80 KDM4E (0.68) ALDH1A1KDM4EHPGDPTGS1POLB
SCHEMBL23918989 0.80 CA9 (0.47) ALDH1A1HSD17B10CFTRNPC1RAB9A
SCHEMBL8663695 0.79 ALDH1A1 (0.54) ALDH1A1HSD17B10CFTRNPC1RAB9A
SCHEMBL23014667 0.79 PTGS1 (0.51) ALDH1A1HSD17B10CFTRNPC1RAB9A
SCHEMBL23356523 0.78 KDM4E (0.66) ALDH1A1HSD17B10NPC1RAB9AGAA
SCHEMBL4465528 0.77 ALDH1A1 (0.49) ALDH1A1HSD17B10NPC1RAB9AGAA
SCHEMBL9921278 0.77 KDM4E (0.60) ALDH1A1HSD17B10CFTRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101258141-B N-thio-anthranilamid compounds and their use as pesticides BASF SE 2012-12-05 CN claimed
CN-101258141-A N-thio-anthranilamid compounds and their use as pesticides BASF AG (DE) 2008-09-03 CN claimed
CN-104768379-A Method of controlling ryanodine-modulator insecticide resistant insects BASF SE 2015-07-08 CN disclosed
CN-104768378-A Use of N-thio-anthranilamide compounds on cultivated plants BASF SE 2015-07-08 CN disclosed
CN-104023724-A N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE 2014-09-03 CN disclosed
CN-103889955-A N-thio-anthranilamide compounds and their use as pesticides BASF SE 2014-06-25 CN disclosed
CN-103857666-A N-thio-anthranilamide compounds and their use as pesticides BASF SE 2014-06-11 CN disclosed
CN-103827092-A N-thio-anthranilamide compounds and their use as pesticides BASF SE 2014-05-28 CN disclosed
CN-103827103-A N-thio-anthranilamide compounds and their use as pesticides BASF SE 2014-05-28 CN disclosed
CN-101258141-B N-thio-anthranilamid compounds and their use as pesticides BASF SE 2012-12-05 CN disclosed
US-7989430-B2 Antibacterial agents REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2011-08-02 US disclosed
US-20080293666-A1 Antibacterial Agents REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2008-11-27 US disclosed
CN-101258141-A N-thio-anthranilamid compounds and their use as pesticides BASF AG (DE) 2008-09-03 CN disclosed
EP-1960518-A2 ANTIBACTERIAL AGENTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2008-08-27 EP disclosed
WO-2007067559-A2 ANTIBACTERIAL AGENTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2007-06-14 WO disclosed
US-4052444-A DIAZO COUPLERS FOR MONOAZO DYES HOECHST AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293666-A1 Antibacterial Agents MRPL21, ABCB7, MSR1 ALDH1A1 1972/4885HSD17B10 2215/4885CFTR 294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.