Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22947692 | 0.89 | L3MBTL1 (0.44) | ALDH1A1TSHRMEN1GLAKMT2A | |
| SCHEMBL22947683 | 0.88 | SMN1; SMN2 (0.41) | ALDH1A1TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22947473 | 0.87 | L3MBTL1 (0.43) | ALDH1A1TSHRMEN1GLAKMT2A | |
| SCHEMBL22949619 | 0.86 | L3MBTL1 (0.47) | ALDH1A1TSHRCYP1A2CYP2C9MEN1 | |
| SCHEMBL22947495 | 0.84 | L3MBTL1 (0.43) | ALDH1A1TSHRCLK4MEN1GLA | |
| SCHEMBL22947715 | 0.84 | L3MBTL1 (0.43) | ALDH1A1TSHRCLK4MEN1GLA | |
| SCHEMBL20222583 | 0.83 | CYP19A1 (0.42) | ALDH1A1TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22949183 | 0.82 | L3MBTL1 (0.41) | ALDH1A1TSHRMEN1GLAKMT2A | |
| SCHEMBL22949685 | 0.81 | L3MBTL1 (0.40) | ALDH1A1TSHRMEN1GLAKMT2A | |
| SCHEMBL22947690 | 0.81 | KDM4E (0.46) | ALDH1A1TSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | ETV6, FES, LEF1 | ALDH1A1 752/4885TSHR 3468/4885CYP1A2 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.