SCHEMBL22950467

SCHEMBL22950467

COc1ccc(-c2ccccc2Cl)c(B(O)O)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
ALOX15 P16050 1/20 0.45
CHEK1 O14757 1/20 0.43
WEE1 P30291 1/20 0.43
CYP1A2 P05177 5/20 0.43
CYP3A4 P08684 4/20 0.43
CYP2C19 P33261 4/20 0.43
CYP2D6 P10635 3/20 0.43
TSHR P16473 3/20 0.43
CLK4 Q9HAZ1 2/20 0.43
MAPK1 P28482 1/20 0.43
GPR3 P46089 1/20 0.42
ENPP2 Q13822 2/20 0.42
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30504305 1.00 KMT2A (0.45) KMT2AMEN1ALOX15CHEK1WEE1
SCHEMBL22949436 0.78 GPR3 (0.46) KMT2AMEN1ALOX15CHEK1WEE1
SCHEMBL28365799 0.78 MIF (0.44) CHEK1WEE1HSD17B10CDK2PDE2A
SCHEMBL2456706 0.78 BACE1 (0.51) KMT2AMEN1CYP1A2CYP3A4CYP2C19
SCHEMBL29469134 0.77 ENPP2 (0.48) KMT2AMEN1CYP1A2MAPK1ENPP2
SCHEMBL41499 0.77 ENPP2 (0.48) KMT2AMEN1CYP1A2MAPK1ENPP2
SCHEMBL22703498 0.77 CYP2A6 (0.44) KMT2ATSHRENPP2NPC1RAB9A
SCHEMBL28366404 0.75 CYP2A6 (0.47) KMT2AMEN1CYP1A2AKR1C3AKR1C2
SCHEMBL31449884 0.73 MEN1 (0.47) KMT2AMEN1ALOX15CHEK1WEE1
SCHEMBL29807652 0.73 ENPP2 (0.48) KMT2AMEN1CYP1A2ENPP2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116102496-A Novel seven-membered heterocyclic compound, application thereof and organic electroluminescent device comprising novel seven-membered heterocyclic compound 合肥鼎材科技有限公司 2023-05-12 CN disclosed
WO-2021018270-A1 HOST COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 浙江华显光电科技有限公司 2021-02-04 WO disclosed