Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295031 | 0.94 | PKM (0.51) | PKMSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL2290352 | 0.92 | SMN1; SMN2 (0.48) | PKMSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL2296261 | 0.87 | PKM (0.47) | PKMSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL2290063 | 0.85 | TSHR (0.43) | PKMSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL2295994 | 0.84 | LMNA (0.47) | PKMLMNAKMT2AHTTCYP2C9 | |
| SCHEMBL2291043 | 0.83 | CNR1 (0.53) | SMN1; SMN2LMNAKMT2AHTTCYP2C9 | |
| SCHEMBL2291074 | 0.83 | LMNA (0.53) | SMN1; SMN2ALDH1A1LMNAKMT2AHTT | |
| SCHEMBL2296179 | 0.82 | PKM (0.49) | PKMSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL2293206 | 0.81 | CNR1 (0.56) | SMN1; SMN2LMNAKMT2AHTTCNR1 | |
| SCHEMBL2292379 | 0.81 | TSHR (0.50) | SMN1; SMN2ALDH1A1POLBLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190300-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2011-08-04 | — | — | US | disclosed |
| US-20110190300-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190300-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | CACNA1E, CACNA1B, CACNA1S | PKM 1843/4885SMN1; SMN2 993/4885ALDH1A1 1349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.