Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31620813 | 1.00 | HSD17B10 (0.47) | HSD17B10TSHRALOX15HTTNPC1 | |
| SCHEMBL2500053 | 0.86 | MAPT (0.56) | HSD17B10TSHRALOX15HTTCA2 | |
| SCHEMBL31236986 | 0.85 | TAAR1 (0.47) | TSHRPOLBCA2ALDH1A1MAPT | |
| SCHEMBL8715027 | 0.85 | TAAR1 (0.47) | TSHRPOLBCA2ALDH1A1MAPT | |
| SCHEMBL23673569 | 0.82 | SLC6A4 (0.42) | HSD17B10TSHRALOX15HTTNPC1 | |
| SCHEMBL17295146 | 0.82 | TNKS2 (0.60) | TSHRPOLBCYP4A11MAPK1TAAR1 | |
| SCHEMBL29887121 | 0.82 | SLC6A4 (0.42) | HSD17B10TSHRALOX15HTTNPC1 | |
| SCHEMBL13698783 | 0.82 | PTGS2 (0.52) | HTTCA2ALDH1A1MAPTHTR2A | |
| SCHEMBL2296988 | 0.82 | CA2 (0.47) | POLBCA2ALDH1A1MAPTHTR2A | |
| SCHEMBL29725217 | 0.82 | CA2 (0.47) | POLBCA2ALDH1A1MAPTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526186-B1 | SUBSTITUTED HYDROXYSTILBENES AND THEIR THERAPEUTIC APPLICATIONS | RESOLVEX PHARMACEUTICALS INC (CA) | 2022-05-04 | — | — | EP | claimed |
| CN-109890784-B | Substituted hydroxystyrenes and therapeutic uses thereof | 瑞泽制药公司 | 2022-04-29 | — | — | CN | claimed |
| EP-3526186-A1 | SUBSTITUTED HYDROXYSTILBENES AND THEIR THERAPEUTIC APPLICATIONS | Resolvex Pharmaceuticals Inc. (CA) | 2019-08-21 | — | — | EP | claimed |
| WO-2018068131-A1 | SUBSTITUTED HYDROXYSTILBENES AND THEIR THERAPEUTIC APPLICATIONS | RESOLVEX PHARMACEUTICALS INC. (CA) | 2018-04-19 | — | — | WO | claimed |
| US-9725406-B1 | Substituted hydroxystilbenes and their therapeutic applications | RESOLVEX PHARMACEUTICALS INC. (CA) | 2017-08-08 | — | — | US | claimed |
| US-12503473-B2 | Triazolopyrimidine compounds and their use in treating cancer | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2025-12-23 | — | — | US | disclosed |
| CN-115151553-B | Boric acid derivatives | 首药控股(北京)股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-118496142-A | Aryl alkylamine compound and preparation method and application thereof | 仁合益康集团有限公司 | 2024-08-16 | — | — | CN | disclosed |
| US-12054660-B2 | Compound, composition, cured substance, optically anisotropic body, optical element, and light guide element | FUJIFILM CORPORATION (JP) | 2024-08-06 | — | — | US | disclosed |
| US-20240217980-A1 | TRIAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE IN TREATING CANCER | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
| EP-3656754-B1 | OLEFIN POLYMERIZATION CATALYST COMPRISING CYCLOTRIVERATRYLENE AND DERIVATIVES THEREOF | CHINA PETROLEUM & CHEM CORP (CN) | 2024-05-29 | — | — | EP | disclosed |
| CN-115028637-B | Triazolopyrimidine compounds and their use for the treatment of cancer | 迪哲(江苏)医药股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |
| EP-0230755-B1 | 1-PHENYL-3-BENZAZEPINES | SMITHKLINE BEECHAM CORPORATION (US) | 1990-05-16 | — | — | EP | disclosed |
| US-4707483-A | 1-phenyl-3-benzazepines and their use for treating gastrointestinal motility disorders | SMITHKLINE BECKMAN CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |
| EP-0244088-A2 | 1-Phenyl-3-benzazepine compounds and medicaments containing these compounds for treating gastrointestinal motility disorders | SMITHKLINE BEECHAM CORPORATION (US) | 1987-11-04 | — | — | EP | disclosed |
| EP-0230755-A1 | 1-Phenyl-3-benzazepines | SMITHKLINE BEECHAM CORPORATION (US) | 1987-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12503473-B2 | Triazolopyrimidine compounds and their use in treating cancer | ABCC4, ABCB1, SLC16A3 | HSD17B10 3684/4885TSHR 1609/4885ALOX15 4446/4885 |
| US-12054660-B2 | Compound, composition, cured substance, optically anisotropic body, optical element, and light guide element | SP1, C5, ZYX | HSD17B10 4588/4885TSHR 4560/4885ALOX15 759/4885 |
| US-20240217980-A1 | TRIAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE IN TREATING CANCER | ABCC4, ABCB1, SLC16A3 | HSD17B10 3684/4885TSHR 1609/4885ALOX15 4446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.