Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | LATS1 | O95835 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15158515 | 0.77 | CYP11B2 (0.46) | CYP11B2MAPK1HIF1A | |
| SCHEMBL21233343 | 0.77 | CYP11B2 (0.51) | CYP11B2BRAFMAPK3MAPK1HIF1A | |
| SCHEMBL22951297 | 0.75 | NPC1 (0.42) | CYP11B2 | |
| SCHEMBL22952451 | 0.74 | CYP11B2 (0.40) | CYP11B2 | |
| SCHEMBL22951312 | 0.73 | CYP11B2 (0.37) | CYP11B2 | |
| SCHEMBL21241317 | 0.73 | CYP11B2 (0.35) | CYP11B2BRAFMAPK3MAPK1HIF1A | |
| SCHEMBL22951419 | 0.73 | CYP11B2 (0.40) | CYP11B2BRAFHIF1A | |
| SCHEMBL22952431 | 0.72 | CYP11B2 (0.39) | CYP11B2 | |
| SCHEMBL22952799 | 0.70 | BRD4 (0.34) | CYP11B2HIF1A | |
| SCHEMBL22678962 | 0.66 | KDM4E (0.32) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210032222-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUNDS AND DERIVATIVES, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND APPLICATIONS THEREOF | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210032222-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUNDS AND DERIVATIVES, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND APPLICATIONS THEREOF | CBR3, CBR1, CYP8B1 | CYP11B2 159/4885BRAF 1212/4885MAPK3 3231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.