Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12304102 | 0.77 | CYP11B2 (0.44) | CYP11B2HIF1ACYP3A4 | |
| SCHEMBL21233343 | 0.77 | CYP11B2 (0.51) | CYP11B2HIF1ABRAFMAPK3MAPK1 | |
| SCHEMBL22952429 | 0.73 | CYP11B2 (0.40) | CYP11B2HIF1ABRAFMAPK3MAPK1 | |
| SCHEMBL2737254 | 0.69 | KDM4E (0.36) | CYP11B2HIF1ACDK1CDK4CCNA2 | |
| SCHEMBL26874447 | 0.67 | TRPA1 (0.45) | HIF1ACYP3A4 | |
| SCHEMBL21241323 | 0.67 | CYP2D6 (0.33) | HIF1AROCK2CYP3A4ROCK1CDK1 | |
| SCHEMBL23399177 | 0.66 | KDM4E (0.31) | — | |
| SCHEMBL21233325 | 0.66 | PHGDH (0.35) | CYP11B2 | |
| SCHEMBL2738301 | 0.66 | ADORA2A (0.41) | HIF1A | |
| SCHEMBL13728814 | 0.65 | PSEN1 (0.36) | ROCK2CYP3A4ROCK1PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |