Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.78 |
| ▸ | DRD2 | P14416 | 1/20 | 0.78 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.78 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.78 |
| ▸ | DRD1 | P21728 | 1/20 | 0.78 |
| ▸ | DRD5 | P21918 | 1/20 | 0.78 |
| ▸ | DRD3 | P35462 | 1/20 | 0.78 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.36 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611683 | 0.88 | DRD1 (1.00) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22952932 | 0.86 | ADRA2A (0.68) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22952996 | 0.84 | DRD1 (0.65) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22952992 | 0.84 | DRD1 (0.65) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22952994 | 0.84 | ADRA2A (0.65) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22953002 | 0.84 | ADRA2A (0.65) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22952936 | 0.82 | DRD1 (0.63) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22952935 | 0.82 | DRD1 (0.54) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22952993 | 0.82 | ADRA2A (0.62) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22953000 | 0.76 | ADRA2A (0.49) | ADRA2ADRD2ADRA2BADRA2CDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021922-A1 | COMPOUNDS AND METHODS FOR TREATING FIBROTIC PATHOLOGIES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-02-04 | — | — | WO | disclosed |