Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 1/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.63 |
| ▸ | DRD5 | P21918 | 1/20 | 0.63 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.31 |
| ▸ | CDK9 | P50750 | 4/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22953002 | 0.88 | ADRA2A (0.65) | DRD1ADRA2ADRD2ADRA2BADRA2C | |
| SCHEMBL22952992 | 0.88 | DRD1 (0.65) | DRD1ADRA2ADRD2ADRA2BADRA2C | |
| SCHEMBL22952932 | 0.87 | ADRA2A (0.68) | DRD1ADRA2ADRD2ADRA2BADRA2C | |
| SCHEMBL22952999 | 0.86 | ADRA2A (0.45) | DRD1ADRA2ADRD2ADRA2BADRA2C | |
| SCHEMBL22953004 | 0.86 | ADRA2A (0.45) | DRD1ADRA2ADRD2ADRA2BADRA2C | |
| SCHEMBL22953003 | 0.86 | ADRA2A (0.45) | DRD1ADRA2ADRD2ADRA2BADRA2C | |
| SCHEMBL22952996 | 0.85 | DRD1 (0.65) | DRD1ADRA2ADRD2ADRA2BADRA2C | |
| SCHEMBL22952994 | 0.85 | ADRA2A (0.65) | DRD1ADRA2ADRD2ADRA2BADRA2C | |
| SCHEMBL22952993 | 0.83 | ADRA2A (0.62) | DRD1ADRA2ADRD2ADRA2BADRA2C | |
| SCHEMBL22952930 | 0.82 | ADRA2A (0.78) | DRD1ADRA2ADRD2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021922-A1 | COMPOUNDS AND METHODS FOR TREATING FIBROTIC PATHOLOGIES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-02-04 | — | — | WO | disclosed |