Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 12/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ALAD | P13716 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15988713 | 0.83 | GSK3B (0.47) | GSK3BCES2CES1ALADALDH1A1 | |
| SCHEMBL10513732 | 0.80 | GSK3B (0.44) | GSK3BCES2CES1ALADALDH1A1 | |
| SCHEMBL13116478 | 0.80 | GSK3B (0.44) | GSK3BCES2CES1ALADALDH1A1 | |
| SCHEMBL15282434 | 0.79 | GSK3B (0.68) | GSK3BCES2CES1ALADALDH1A1 | |
| Hydrochloric Acid SCHEMBL4266714 | 0.78 | GSK3B (0.43) | GSK3BCES2CES1ALADALDH1A1 | |
| SCHEMBL27577455 | 0.77 | GSK3B (0.42) | GSK3BALADALDH1A1LMNAMAPT | |
| SCHEMBL31000806 | 0.76 | CES2 (0.56) | GSK3BCES2CES1ALADALDH1A1 | |
| SCHEMBL15547606 | 0.76 | DAO (0.59) | GSK3BCES2CES1ALDH1A1LMNA | |
| SCHEMBL19638058 | 0.76 | GSK3B (0.41) | GSK3BALADMAPTMEN1KMT2A | |
| SCHEMBL7813005 | 0.74 | GSK3B (0.52) | GSK3BCES2CES1ALADPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865951-A | Method for preparing 4- (4-chloro-2-thienyl) -2-thiazolamine | 苏州健雄职业技术学院 | 2024-04-12 | — | — | CN | disclosed |
| WO-2021021000-A1 | METHOD FOR PRODUCING AVATROMBOPAG | ФАЗЫЛОВ, Марат Феликсович | 2021-02-04 | — | — | WO | disclosed |