Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 5/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 5/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336494 | 0.84 | ALDH1A1 (0.45) | ALDH1A1RAB9AMAPTSMN1; SMN2SCN1A | |
| SCHEMBL12049806 | 0.82 | ALDH1A1 (0.41) | ALDH1A1RAB9AMAPTSMN1; SMN2SCN1A | |
| SCHEMBL13867376 | 0.81 | RAB9A (0.46) | ALDH1A1RAB9AMAPTSMN1; SMN2SCN1A | |
| SCHEMBL27429200 | 0.81 | PAOX (0.41) | ALDH1A1RAB9AMAPTSMN1; SMN2SCN1A | |
| SCHEMBL16488085 | 0.80 | ALDH1A1 (0.36) | ALDH1A1RAB9AMAPTSMN1; SMN2SCN1A | |
| SCHEMBL27397480 | 0.79 | ALDH1A1 (0.39) | ALDH1A1RAB9AMAPTSMN1; SMN2SCN1A | |
| SCHEMBL12030708 | 0.79 | HRH3 (0.40) | KCNH2 | |
| SCHEMBL12312684 | 0.79 | ATM (0.37) | CHRM3ATMCHRM2 | |
| SCHEMBL18502887 | 0.79 | CHRM3 (0.40) | ALDH1A1RAB9AMAPTSMN1; SMN2SCN1A | |
| SCHEMBL12049969 | 0.79 | ALDH1A1 (0.39) | ALDH1A1RAB9AMAPTSMN1; SMN2SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126617-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING KINASES VIA UBIQUITIN PROTEOSOME PATHWAY | CROSSFIRE ONCOLOGY HOLDING B.V. (NL) | 2024-06-20 | — | — | WO | disclosed |
| WO-2021018118-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1 PROTEINS | JANSSEN PHARMACEUTICA NV (BE) | 2021-02-04 | — | — | WO | disclosed |