SCHEMBL22955

SCHEMBL22955

CCCCCCCCCCCCCCCCCCOC(=O)C(N)CCCCN

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.56
GNAO1 P09471 1/20 0.56
GNAI1 P63096 1/20 0.56
TLR2 O60603 2/20 0.53
NOD1 Q9Y239 2/20 0.53
GSR P00390 1/20 0.47
NAAA Q02083 1/20 0.46
DPP8 Q6V1X1 1/20 0.46
DPP9 Q86TI2 1/20 0.46
DPP7 Q9UHL4 1/20 0.46
HTR2C P28335 1/20 0.45
CPB2 Q96IY4 1/20 0.44
RRM1 P23921 1/20 0.44
DNM1 Q05193 4/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
EPHX1 P07099 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22956 1.00 GNAI3 (0.56) GNAI3GNAO1GNAI1TLR2NOD1
SCHEMBL10613585 1.00 GNAI3 (0.56) GNAI3GNAO1GNAI1TLR2NOD1
SCHEMBL10611658 1.00 GNAI3 (0.56) GNAI3GNAO1GNAI1TLR2NOD1
SCHEMBL285284 1.00 GNAI3 (0.56) GNAI3GNAO1GNAI1TLR2NOD1
SCHEMBL7771135 1.00 GNAI3 (0.56) GNAI3GNAO1GNAI1TLR2NOD1
SCHEMBL10614116 1.00 GNAI3 (0.56) GNAI3GNAO1GNAI1TLR2NOD1
SCHEMBL5267100 1.00 GNAI3 (0.56) GNAI3GNAO1GNAI1TLR2NOD1
SCHEMBL10611883 1.00 GNAI3 (0.56) GNAI3GNAO1GNAI1TLR2NOD1
SCHEMBL10609973 1.00 GNAI3 (0.56) GNAI3GNAO1GNAI1TLR2NOD1
SCHEMBL10612555 1.00 GNAI3 (0.56) GNAI3GNAO1GNAI1TLR2NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120196873-A1 STABILIZATION OF AMORPHOUS DRUGS USING SPONGE-LIKE CARRIER MATRICES CAPSULUTION NANOSCIENCE AG 2012-08-02 US claimed
WO-2012101242-A1 NOVEL PHARMACEUTICAL SUSPENSION FOR PARENTERAL APPLICATION CAPSULUTION PHARMA AG (DE) 2012-08-02 WO claimed
US-20120058151-A1 NANOPARTICULATE COMPOSITIONS OF POORLY SOLUBLE COMPOUNDS CAPSULUTION PHARMA AG 2012-03-08 US claimed
EP-2349229-A1 IMPROVED NANOPARTICULATE COMPOSITIONS OF POORLY SOLUBLE COMPOUNDS Capsulution Pharma AG (DE) 2011-08-03 EP claimed
EP-2303235-A2 STABILIZATION OF AMORPHOUS DRUGS USING SPONGE-LIKE CARRIER MATRICES Capsulution NanoScience AG (DE) 2011-04-06 EP claimed
WO-2010037566-A1 IMPROVED NANOPARTICULATE COMPOSITIONS OF POORLY SOLUBLE COMPOUNDS CAPSULUTION PHARMA AG (DE) 2010-04-08 WO claimed
EP-2172193-A1 Improved nanoparticulate compositions of poorly soluble compounds Capsulution Nanoscience AG (DE) 2010-04-07 EP claimed
EP-2135601-A1 Stabilization of amorphous drugs using sponge-like carrier matrices Capsulution Nanoscience AG (DE) 2009-12-23 EP claimed
WO-2009153346-A2 STABILIZATION OF AMORPHOUS DRUGS USING SPONGE-LIKE CARRIER MATRICES CAPSULUTION NANOSCIENCE AG (DE) 2009-12-23 WO claimed
EP-1920257-A1 OPTICALLY FLUORESCENT NANOPARTICLES Bayer Schering Pharma AG (DE) 2008-05-14 EP claimed
US-20070104649-A1 Optically fluorescent nanoparticles SCHERING AG (DE) 2007-05-10 US claimed
WO-2007025768-A1 OPTICALLY FLUORESCENT NANOPARTICLES BAYER SCHERING PHARMA AG (DE) 2007-03-08 WO claimed
EP-1760467-A1 Optically fluorescent nanoparticles Schering AG (DE) 2007-03-07 EP claimed
US-5700459-A POLYBASE AND POLYACID, ONE OF WHICH IS A POLYMER, ACTIVE MATERIAL COMPRISING ANTIINFLAMMATORY AGENT, ANTIBIOTIC, ENZYME INHIBITOR HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-23 US claimed
EP-0454044-B1 Pharmacological product containing polyelectrolyte complexes in microparticulate form and at least one substance HOECHST AG (DE) 1995-12-06 EP claimed
EP-2608774-A1 POROUS DEGRADABLE POLYELECTROLYTE MICROSPHERES AS VACCINE VECTOR Universiteit Gent (BE) 2013-07-03 EP disclosed
US-20130149357-A1 Porous Degradable Polyelectrolyte Microspheres as Vaccine Vector UNIVERSITEIT GENT (BE) 2013-06-13 US disclosed
EP-0162747-B1 LYSINE ESTERS USED AS ABSORPTION ENHANCING AGENTS MERCK & CO. INC. (US) 1988-12-07 EP disclosed
US-4749694-A ENHANCING AGENTS FOR GASTROINTESTINALLY AND RECTALLY ADMINISTEAED DRUGS MERCK & CO., INC. (US) 1988-06-07 US disclosed
EP-0162747-A1 Lysine esters used as absorption enhancing agents MERCK & CO. INC. (US) 1985-11-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130149357-A1 Porous Degradable Polyelectrolyte Microspheres as Vaccine Vector CMA1, ADAM33, MME GNAI3 4377/4885GNAO1 4735/4885GNAI1 4260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.