Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29808445 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AKDM4ECYP1A2 | |
| SCHEMBL22956031 | 0.92 | CNR2 (0.46) | SMN1; SMN2NPC1RAB9AKDM4ECYP1A2 | |
| SCHEMBL22955295 | 0.89 | RAB9A (0.62) | SMN1; SMN2NPC1RAB9AKDM4ECYP1A2 | |
| SCHEMBL22955320 | 0.87 | CNR2 (0.44) | SMN1; SMN2NPC1RAB9AKDM4ECYP1A2 | |
| SCHEMBL22955440 | 0.86 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AKDM4ECYP1A2 | |
| SCHEMBL22955328 | 0.86 | CNR2 (0.46) | SMN1; SMN2NPC1RAB9AKDM4ECYP1A2 | |
| SCHEMBL22956051 | 0.83 | SERPINE1 (0.43) | SMN1; SMN2NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL29808602 | 0.83 | CNR2 (0.58) | SMN1; SMN2NPC1RAB9AKDM4ECYP1A2 | |
| SCHEMBL22956032 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AKDM4ECYP1A2 | |
| SCHEMBL22955467 | 0.82 | GRM2 (0.44) | SMN1; SMN2NPC1RAB9AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022061-A1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | OREGON STATE UNIVERSITY (US) | 2021-02-04 | — | — | WO | disclosed |