Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22955900 | 0.89 | MAOB (0.39) | CNR2MAPTMAPK1CYP2C9 | |
| SCHEMBL22955293 | 0.87 | SMN1; SMN2 (0.51) | CNR2ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL29808445 | 0.87 | SMN1; SMN2 (0.51) | CNR2ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL22955328 | 0.83 | CNR2 (0.46) | CNR2ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL22956031 | 0.82 | CNR2 (0.46) | CNR2ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL22955467 | 0.82 | GRM2 (0.44) | MAPK1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL22956057 | 0.81 | PGR (0.43) | CNR2ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL22955434 | 0.81 | CNR2 (0.44) | CNR2ALDH1A1HTTCYP1A2CYP2C9 | |
| SCHEMBL22955440 | 0.81 | SMN1; SMN2 (0.55) | CNR2ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL22955903 | 0.80 | POLB (0.41) | CNR2HTTMAPTMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022061-A1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | OREGON STATE UNIVERSITY (US) | 2021-02-04 | — | — | WO | disclosed |