Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22956058 | 0.94 | KDM4E (0.47) | RAB9ASMN1; SMN2NPC1KDM4ECYP1A2 | |
| SCHEMBL22955328 | 0.91 | CNR2 (0.46) | RAB9ASMN1; SMN2NPC1KDM4ECYP1A2 | |
| SCHEMBL22955903 | 0.88 | POLB (0.41) | RAB9ASMN1; SMN2NPC1KDM4ECYP1A2 | |
| SCHEMBL22955295 | 0.86 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1KDM4ECYP1A2 | |
| SCHEMBL22955416 | 0.85 | RAB9A (0.52) | RAB9ASMN1; SMN2NPC1KDM4ECYP1A2 | |
| SCHEMBL22956057 | 0.85 | PGR (0.43) | RAB9ASMN1; SMN2NPC1KDM4ECYP1A2 | |
| SCHEMBL22956056 | 0.83 | SMN1; SMN2 (0.39) | RAB9ASMN1; SMN2NPC1KDM4ECYP1A2 | |
| SCHEMBL22955852 | 0.82 | KDM4E (0.39) | RAB9ASMN1; SMN2NPC1KDM4ECYP1A2 | |
| SCHEMBL22955554 | 0.82 | CHRM5 (0.41) | RAB9ASMN1; SMN2NPC1KDM4ECYP1A2 | |
| SCHEMBL22956045 | 0.81 | PGR (0.43) | RAB9ASMN1; SMN2NPC1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022061-A1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | OREGON STATE UNIVERSITY (US) | 2021-02-04 | — | — | WO | disclosed |