Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 3/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | RHEB | Q15382 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27824953 | 0.80 | HPGD (0.47) | HPGDSMN1; SMN2LMNANPC1ALDH1A1 | |
| SCHEMBL2313456 | 0.80 | MAPK10 (0.46) | MAPK10METAP2METAP1CHEK2PKN1 | |
| SCHEMBL29824703 | 0.79 | MAPK13 (0.51) | MAPK10METAP2METAP1HPGDSMN1; SMN2 | |
| SCHEMBL22955599 | 0.79 | MAPK13 (0.51) | MAPK10METAP2METAP1HPGDSMN1; SMN2 | |
| SCHEMBL29824605 | 0.79 | NPC1 (0.49) | METAP2METAP1HPGDSMN1; SMN2RHEB | |
| SCHEMBL2951537 | 0.79 | NPC1 (0.49) | METAP2METAP1HPGDSMN1; SMN2RHEB | |
| SCHEMBL22955874 | 0.79 | ALDH1A1 (0.52) | METAP2METAP1HPGDSMN1; SMN2LMNA | |
| SCHEMBL22955429 | 0.79 | PTGES (0.49) | HPGDSMN1; SMN2LMNANPC1ALDH1A1 | |
| SCHEMBL16148264 | 0.79 | ATR (0.49) | CHEK2HPGDSMN1; SMN2RHEBLMNA | |
| SCHEMBL28267390 | 0.79 | CHEK2 (0.61) | MAPK10METAP2METAP1CHEK2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022061-A1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | OREGON STATE UNIVERSITY (US) | 2021-02-04 | — | — | WO | disclosed |