Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23239891 | 0.80 | MCL1 (0.39) | KDM4EHSD17B10HPGDNPC1RAB9A | |
| SCHEMBL31318489 | 0.78 | KDM4E (0.51) | KDM4EHSD17B10HPGDNPC1RAB9A | |
| SCHEMBL26376827 | 0.71 | KDM4E (0.48) | KDM4EHSD17B10HPGDNPC1RAB9A | |
| SCHEMBL7670850 | 0.71 | PTPN1 (0.41) | MCL1JAK3 | |
| SCHEMBL26385151 | 0.70 | KDM4E (0.50) | KDM4EHSD17B10HPGDNPC1RAB9A | |
| SCHEMBL17809894 | 0.70 | MCL1 (0.40) | KDM4EMCL1ALDH1A1 | |
| SCHEMBL17348607 | 0.69 | KDM4E (0.50) | KDM4EMCL1ALDH1A1KMT2A | |
| SCHEMBL20340618 | 0.69 | MCL1 (0.42) | HPGDNPC1RAB9ASMN1; SMN2MCL1 | |
| SCHEMBL24527794 | 0.67 | MAOA (0.42) | KDM4ETP53TSHRMCL1MAPT | |
| SCHEMBL26384875 | 0.67 | ADRA1D (0.43) | KDM4EHSD17B10HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022061-A1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | OREGON STATE UNIVERSITY (US) | 2021-02-04 | — | — | WO | disclosed |