Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22955655 | 0.93 | DRD2 (0.51) | DRD2TBXA2RPTGER4ENPP2LMNA | |
| SCHEMBL22955497 | 0.91 | DRD2 (0.62) | DRD2TBXA2RPTGER4ENPP2PPARG | |
| SCHEMBL22955895 | 0.91 | DRD2 (0.49) | DRD2TBXA2RPTGER4ENPP2PPARG | |
| SCHEMBL22955358 | 0.89 | ENPP2 (0.49) | DRD2TBXA2RPTGER4ENPP2PPARG | |
| SCHEMBL22955362 | 0.84 | DRD2 (0.62) | DRD2TBXA2RPTGER4ENPP2MAPT | |
| SCHEMBL22955691 | 0.83 | DRD2 (0.49) | DRD2TBXA2RPTGER4ENPP2CFTR | |
| SCHEMBL22955618 | 0.83 | CNR2 (0.51) | PTGER4LMNAMAPTKMT2APOLB | |
| SCHEMBL2161533 | 0.82 | KDM4E (0.68) | PPARGKDM4ELMNAMAPTTP53 | |
| SCHEMBL22955585 | 0.81 | PTGER4 (0.48) | PTGER4MAPTKMT2A | |
| SCHEMBL2100541 | 0.80 | KDM4E (0.55) | DRD2TBXA2RPPARGKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022061-A1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | OREGON STATE UNIVERSITY (US) | 2021-02-04 | — | — | WO | disclosed |