Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3169656 | 0.90 | TDP1 (0.60) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL22956070 | 0.87 | F2 (0.44) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL22955365 | 0.85 | SMN1; SMN2 (0.54) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL31429585 | 0.84 | F2 (0.55) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL12471073 | 0.84 | F2 (0.55) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL17275548 | 0.83 | RAB9A (0.60) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL22955364 | 0.81 | HPGD (0.55) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL828113 | 0.81 | KDM4E (0.56) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL2309903 | 0.81 | RAB9A (0.50) | RAB9AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL8611783 | 0.80 | KDM4E (0.69) | RAB9AKDM4EALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022061-A1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | OREGON STATE UNIVERSITY (US) | 2021-02-04 | — | — | WO | disclosed |