Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 13/20 | 0.63 |
| ▸ | NPY4R | P50391 | 7/20 | 0.54 |
| ▸ | NPY1R | P25929 | 4/20 | 0.54 |
| ▸ | NPY2R | P49146 | 2/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21886580 | 1.00 | OPRK1 (0.63) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL11931981 | 0.97 | OPRK1 (0.62) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL21286615 | 0.94 | OPRK1 (0.59) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL17132175 | 0.94 | OPRK1 (0.58) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL17706582 | 0.93 | OPRK1 (0.60) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL12317349 | 0.93 | OPRK1 (0.59) | OPRK1OPRM1 | |
| SCHEMBL22957114 | 0.91 | OPRK1 (0.56) | OPRK1NPY4RNPY1ROPRM1 | |
| SCHEMBL11931484 | 0.89 | OPRK1 (0.78) | OPRK1OPRM1 | |
| SCHEMBL21286478 | 0.89 | OPRK1 (0.79) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL19249337 | 0.88 | OPRK1 (0.81) | OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913769-B2 | Synthetic peptide amides and dimers thereof | CARA THERAPEUTICS, INC. (US) | 2021-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913769-B2 | Synthetic peptide amides and dimers thereof | OPRK1, OPRL1, OPRM1 | OPRK1 1/4885NPY4R 46/4885NPY1R 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.