Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 6/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19297276 | 0.84 | RBP4 (0.40) | RBP4RIPK1 | |
| SCHEMBL16118522 | 0.82 | RBP4 (0.36) | RBP4RIPK1CYP2C19 | |
| SCHEMBL19413393 | 0.80 | RBP4 (0.35) | RBP4RIPK1CYP2C19 | |
| SCHEMBL16123831 | 0.80 | RBP4 (0.36) | RBP4RIPK1CYP2C19 | |
| SCHEMBL19297272 | 0.76 | CYP2C19 (0.51) | CYP2C19 | |
| SCHEMBL17232839 | 0.73 | RBP4 (0.41) | RBP4RIPK1CYP2C19 | |
| SCHEMBL22958125 | 0.71 | CYP2C19 (0.36) | RBP4CYP2C19 | |
| SCHEMBL17229736 | 0.71 | RBP4 (0.40) | RBP4RIPK1CYP2C19 | |
| SCHEMBL19831877 | 0.71 | CREBBP (0.44) | — | |
| SCHEMBL24045537 | 0.70 | RIPK1 (0.43) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913746-B2 | Substituted 4-phenylpiperidines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913746-B2 | Substituted 4-phenylpiperidines, their preparation and use | HRH4, HRH3, HRH2 | RBP4 1884/4885RIPK1 4067/4885CYP2C19 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.